Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults
Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Oct 4, 2023
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking into how using high potency THC products, like strong cannabis concentrates, affects the thinking and memory skills of young adults aged 21 to 25. The main goal is to find out if switching to less potent THC products can help improve cognitive function in regular cannabis users. Researchers also want to explore how well they can measure THC use, whether genetic factors play a role in how THC is processed in the body, and how these factors might relate to cognitive performance and urinary THC levels.
To participate, you need to be between 21 and 25 years old, live in San Francisco, and use cannabis concentrates almost daily from regulated stores in California. If you join the study, you'll provide blood and urine samples and be encouraged to try less potent THC products, with some incentives offered to support this change. The study is currently recruiting participants, and it’s important to note that pregnant individuals or those who regularly use other drugs (besides nicotine) cannot participate.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Between the ages of 21-25
- • Resides in San Francisco
- • Self-report cannabis concentrate use as their primary method of cannabis use
- • Self-report using cannabis daily or almost daily (i.e., at least 6 out of 7 days during each of the last 4 weeks)
- • Self-report only purchasing cannabis from regulated retail stores in California.
- Exclusion Criteria:
- • Pregnant
- • Regularly uses other drugs (other than nicotine)
About University Of California, San Francisco
The University of California, San Francisco (UCSF) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into effective therapies, UCSF collaborates with a diverse array of stakeholders, including healthcare professionals, industry partners, and patient communities. The university's research programs emphasize interdisciplinary approaches and leverage cutting-edge technology to address complex medical challenges. As a sponsor of clinical trials, UCSF is dedicated to maintaining the highest standards of ethical conduct and scientific rigor, ensuring the safety and well-being of participants while contributing to the broader medical knowledge base.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
San Francisco, California, United States
San Francisco, California, United States
Patients applied
Trial Officials
Veronika Mesheriakova, MD
Principal Investigator
University of California, San Francisco
Michael Sofis, PhD
Principal Investigator
Cannabis Public Policy Consulting
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported