ClinConnect ClinConnect Logo
Search / Trial NCT06077292

Cannabis THC Potency, Metabolism, and Cognitive Impairment in Young Adults

Launched by UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · Oct 4, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Cannabis Marijuana High Potency Thc Dabs Wax Young Adult Youth

ClinConnect Summary

This clinical trial is looking into how using high potency THC products, like strong cannabis concentrates, affects the thinking and memory skills of young adults aged 21 to 25. The main goal is to find out if switching to less potent THC products can help improve cognitive function in regular cannabis users. Researchers also want to explore how well they can measure THC use, whether genetic factors play a role in how THC is processed in the body, and how these factors might relate to cognitive performance and urinary THC levels.

To participate, you need to be between 21 and 25 years old, live in San Francisco, and use cannabis concentrates almost daily from regulated stores in California. If you join the study, you'll provide blood and urine samples and be encouraged to try less potent THC products, with some incentives offered to support this change. The study is currently recruiting participants, and it’s important to note that pregnant individuals or those who regularly use other drugs (besides nicotine) cannot participate.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Between the ages of 21-25
  • Resides in San Francisco
  • Self-report cannabis concentrate use as their primary method of cannabis use
  • Self-report using cannabis daily or almost daily (i.e., at least 6 out of 7 days during each of the last 4 weeks)
  • Self-report only purchasing cannabis from regulated retail stores in California.
  • Exclusion Criteria:
  • Pregnant
  • Regularly uses other drugs (other than nicotine)

About University Of California, San Francisco

The University of California, San Francisco (UCSF) is a leading academic institution renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a focus on translating scientific discoveries into effective therapies, UCSF collaborates with a diverse array of stakeholders, including healthcare professionals, industry partners, and patient communities. The university's research programs emphasize interdisciplinary approaches and leverage cutting-edge technology to address complex medical challenges. As a sponsor of clinical trials, UCSF is dedicated to maintaining the highest standards of ethical conduct and scientific rigor, ensuring the safety and well-being of participants while contributing to the broader medical knowledge base.

Locations

San Francisco, California, United States

San Francisco, California, United States

Patients applied

0 patients applied

Trial Officials

Veronika Mesheriakova, MD

Principal Investigator

University of California, San Francisco

Michael Sofis, PhD

Principal Investigator

Cannabis Public Policy Consulting

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported