Prediction of Hypotension During Induction of General Anesthesia

Launched by AIN SHAMS UNIVERSITY · Oct 5, 2023

Keywords

ClinConnect Summary

This is an observational study from Ain Shams University in Cairo that is checking whether simple ultrasound measurements taken before anesthesia can predict low blood pressure (hypotension) after anesthesia is given. Doctors will look at two ultrasound measurements—the carotid artery flow time and the collapsibility of the internal jugular vein—to see if they help forecast who might develop hypotension during induction. The study is designed as a prospective cohort, following participants over a one-year window for this outcome.

You might be eligible if you are an adult aged 18–65, generally healthy (ASA I–II), having an elective surgery that will use general anesthesia, and you have a body mass index under 40. There are several exclusion criteria, such as certain heart, kidney, or liver conditions, significant heart failure or valve disease, preexisting neck vascular issues, or other factors the doctors believe could affect the ultrasound measurements. If enrolled, you would have preoperative ultrasound measurements and then receive the usual anesthesia medicines (like propofol, fentanyl, and atracurium) during the procedure. The study is not testing a new treatment; it is just observing and recording data to see if these ultrasound tests can predict hypotension. As of now, results have not been published yet, and enrollment is ongoing.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1- Patients of American Society of Anesthesiologists (ASA) physical status I to II of both genders.
• • 2- Aged 18-65 years. 3- Elective surgeries under general anesthesia. 4- BMI less than 40.
• Exclusion Criteria:
• • Patients with
• • 1. Renal diseases.
• • 2. Hepatic diseases.
• • 3. ASA scores of 3-4.
• • 4. The presence of a left ventricular ejection fraction less than 50%.
• • 5. Age under 18 years old.
• • 6. Patient refusal.
• • 7. Coronary heart disease.
• • 8. Cardiac disease including cardiomyopathy and mild to severe valve disease.
• • 9. Pulmonary hypertension.
• • 10. Peripheral arterial disease.
• • 11. Preoperative cervical vascular ultrasound abnormalities including plaque, stenosis and anatomical variation.
• • 12. Any previous neck surgery or trauma.