Sexual Function and Quality of Life After LEEP: a Prospective Multi-Center Study
Launched by TAMPERE UNIVERSITY HOSPITAL · Oct 5, 2023
Trial Information
Current as of June 26, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how a specific medical procedure called LEEP, used to treat cervical dysplasia (abnormal cell changes in the cervix due to HPV), affects women's sexual function and overall quality of life. Researchers want to find out if women who undergo LEEP experience any changes in their sexual health or quality of life compared to women who do not have this procedure but only attend regular check-ups. Participants will answer questionnaires about their sexual function and quality of life at different points in time: when they first see the doctor, and then again at 6 months, 2 years, 3 years, and 5 years after their initial visit.
To participate in the study, women need to be between 18 and 70 years old, sexually active, and fluent in Finnish. They must be visiting for the first time for a colposcopy (a type of exam for cervical health) and not have had any previous LEEP or surgeries that could affect the cervix. Participants will fill out online questionnaires at various times to help researchers learn more about their experiences before and after the treatment. This study is currently recruiting participants, and your involvement could help improve understanding of the effects of LEEP on women's health.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Age 18 to 70 years
- • First colposcopy visit (in 24 months, if previous colposcopies)
- • Referral for cytological changes or repeated HPV positivity
- • No previous LEEP or other operations affecting the length of cervix
- • Not pregnant at the time of colposcopy/LEEP
- • Sexually active
- • Capable of understanding the study protocol - informed consent given
- • Fluent in Finnish
- Exclusion Criteria:
- • Age less than 18 or more than 70 years
- • Previous colposcopy within 24 months
- • Referral for other reason, e.g. vulvar lesion
- • Previous LEEP or other operation affecting the length of cervix
- • Pregnant at the time of colposcopy/LEEP
- • Sexually inactive
- • Unable to understand the study protocol - no informed consent
- • Difficulties in understanding Finnish
About Tampere University Hospital
Tampere University Hospital (TAYS) is a leading academic medical center in Finland, renowned for its commitment to advancing healthcare through innovative research and clinical trials. As a prominent sponsor of clinical studies, TAYS integrates cutting-edge medical practices with rigorous scientific investigation, focusing on improving patient outcomes and enhancing treatment modalities across various specialties. The hospital collaborates with a network of researchers, healthcare professionals, and academic institutions to foster a multidisciplinary approach to medical research, ensuring that findings are translated into real-world applications for the benefit of patients and the broader healthcare community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Helsinki, , Finland
Oulu, , Finland
Kuopio, , Finland
Tampere, , Finland
Tampere, , Finland
Joensuu, , Finland
Patients applied
Trial Officials
Laura Kotaniemi-Talonen, PhD
Principal Investigator
Tampere University Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported