Development of Novel Gastric Cancer Screening and Diagnosis Technologies Using Tongue Imaging and Study of Tongue Image Changes Mechanisms

Launched by ZHEJIANG CANCER HOSPITAL · Oct 5, 2023

Keywords

ClinConnect Summary

This clinical trial is investigating new ways to detect gastric cancer by looking at images of the tongue and studying changes in the tongue’s appearance. The researchers aim to gather information from 100,000 people, including those diagnosed with gastric cancer who haven’t received any treatment yet, as well as healthy individuals. By combining tongue images with data from saliva and stool samples, they hope to create a better method for diagnosing gastric cancer and to understand how the bacteria in our mouths and intestines might relate to the disease.

To be eligible for the study, gastric cancer patients need to be between 18 and 90 years old, have a confirmed diagnosis of gastric cancer, and not have received any cancer treatments before. Healthy participants also need to be within this age range and willing to join the study. Throughout the trial, participants will be asked to provide their consent and cooperate during follow-ups. It's important to note that individuals with certain health conditions or recent use of specific medications may not qualify for the study. Overall, this research could lead to improved screening methods for gastric cancer, helping identify the disease earlier and more effectively.

Gender

ALL

Eligibility criteria

• Inclusion Criteria for Gastric Cancer Patients:
• • 18≤age≤90
• • Histologically or cytologically confirmed gastric cancer
• • No prior chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor treatment for gastric cancer
• • Subject volunteers to join the study, Signs informed consent, has good compliance and can cooperate with follow-up
• Exclusion Criteria for Gastric Cancer Patients:
• • Two or more kinds of malignant tumors at the same time
• • Gastric cancer that has been treated by chemotherapy, radiotherapy, biotherapy, immunotherapy or other anti-tumor therapy
• • The use of glucocorticoids and antibiotics in the past three months
• • History of long-term medication
• • Presence of oral diseases such as tooth and gum diseases
• • Subjects who had other factors that might force them to terminate the research ahead of time, such as the development of other severe disease (including mental disease) that required combined treatment, seriously abnormal laboratory examination value, and family or social factors that might affect the subject safety or experimental data collection, as judged by the researchers
• Inclusion Criteria for Healthy Participants:
• • 18≤age≤90
• • Willingness to participate in the study, signing an informed consent form, and demonstrating good compliance
• Exclusion Criteria for Healthy Participants:
• • History of malignant tumors
• • The use of glucocorticoids and antibiotics in the past three months
• • History of long-term medication
• • Presence of oral diseases such as tooth and gum diseases
• • Subjects who had other factors that might force them to terminate the research ahead of time, such as the development of other severe disease (including mental disease) that required combined treatment, seriously abnormal laboratory examination value, and family or social factors that might affect the subject safety or experimental data collection, as judged by the researchers