Multiple Micronutrient Supplementation for Maternal Anemia Prevention in Tanzania
Launched by GEORGE WASHINGTON UNIVERSITY · Oct 6, 2023
Trial Information
Current as of July 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at the effects of different types of multiple micronutrient supplements (MMS) on preventing anemia in pregnant women in Tanzania. Anemia is a condition where you don’t have enough healthy red blood cells, which can be more common during pregnancy. The study will compare two types of MMS that contain different amounts of iron to see which one works better for preventing moderate or severe anemia in mothers-to-be.
To join this study, participants need to be pregnant women who are less than 20 weeks along, at least 18 years old, and planning to stay in Dar es Salaam until six weeks after giving birth. They should also be visiting the clinic for their first prenatal check-up. However, women with severe anemia or certain blood disorders, like sickle cell disease, cannot participate. If you join the trial, you will receive either the standard MMS or the new formulation, and the results will help improve care for pregnant women in Tanzania and similar regions.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Attending first ANC visit at study clinics
- • Pregnant women \< 20 weeks gestation by last menstrual period (LMP)
- • Aged ≥ 18 years old
- • Intending to stay in Dar es Salaam until 6 weeks post delivery
- • Provides informed consent
- Exclusion Criteria:
- • Severe anemia (defined as hemoglobin \< 8.5 g/dL per Tanzania standard of care)
- • Sickle cell disease (SS and SC) and hemoglobin C disease (CC) as tested by HemoTypeSC
- • Concurrently enrolled in another nutritional clinical trial
- • Pregnant women with disability or condition which would impair their ability to provide informed consent and complete study procedures.
About George Washington University
George Washington University (GWU) is a leading academic institution dedicated to advancing medical research and education. As a clinical trial sponsor, GWU leverages its extensive resources and expertise to facilitate innovative studies that aim to improve healthcare outcomes. The university's commitment to ethical research practices, collaboration with multidisciplinary teams, and engagement with diverse populations underscores its role in addressing critical health challenges. By fostering a rigorous scientific environment, GWU strives to translate research findings into effective clinical applications, ultimately enhancing patient care and contributing to the broader medical community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Dar Es Salaam, , Tanzania
Patients applied
Trial Officials
Blair Wylie, MD, MPH
Principal Investigator
Columbia University
Honorati Masanja, PhD
Principal Investigator
Ifakara Health Institute
Alfa Muhihi, MD, MPH
Principal Investigator
Africa Academy for Public Health
Andrea Pembe, MD, MMed, PhD, FCOG
Principal Investigator
Muhimbili University of Health and Allied Sciences
Emily R Smith, ScD, MPH
Principal Investigator
The Goerge Washington University
Christopher R Sudfeld, ScD, ScM
Principal Investigator
Harvard University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported