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Search / Trial NCT06080763

Biomechanics and Clinical Outcomes in Responders and Non-Responders

Launched by MAHIDOL UNIVERSITY · Oct 6, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Biomechanics Assessment, Outcomes

ClinConnect Summary

This clinical trial is looking at why some people with knee osteoarthritis improve after physical therapy while others do not. Knee osteoarthritis is a condition where the cartilage in the knee joint wears down, causing pain and limited movement, especially in older adults. The researchers want to understand the differences in movement and physical function between those who respond well to treatment and those who do not.

To participate, you need to be between 18 and 65 years old, have a diagnosis of knee osteoarthritis, and experience pain rated at least a 4 out of 10. You should also be able to walk at least six meters without help. Before joining the study, you'll receive detailed information about what to expect, including completing questionnaires and undergoing assessments that are commonly used in clinics. This trial is currently recruiting participants, and it aims to help improve treatment options for knee osteoarthritis in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Diagnosis of knee osteoarthritis based on American College of Rheumatology
  • Pain intensity of ≥ 4 out of 10 at the pre-treatment day
  • Ability to walk for at least six meters without an assistive device
  • Exclusion Criteria:
  • History of previous lower limb surgery, such as total hip replacement
  • History of neurological disorder, such as stroke
  • History of vestibular disease, such as Meniere's disease

About Mahidol University

Mahidol University, a premier institution in Thailand, is dedicated to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the university leverages its extensive expertise in medical and health sciences to facilitate rigorous scientific investigations aimed at improving patient care and public health outcomes. With a commitment to ethical practices and collaboration, Mahidol University fosters multidisciplinary approaches, engaging a diverse array of researchers and healthcare professionals to drive meaningful advancements in clinical research.

Locations

Bangkok, Bang Phlat, Thailand

Nakhon Pathom, Salaya, Thailand

Patients applied

0 patients applied

Trial Officials

Komsak Sinsurin, Ph.D.

Principal Investigator

Biomechanics and Sports Research unit, Faculty of Physical Therapy, Mahidol University

Phunsuk Kantha, Ph.D.

Principal Investigator

Faculty of Physical Therapy, Mahidol University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported