Personalized Signature of Chronic Inflammation and Early Aging Predictive of the Comorbidities in Infertile Men
Launched by IRCCS SAN RAFFAELE · Oct 9, 2023
Trial Information
Current as of July 24, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying male infertility, specifically looking at how chronic inflammation and early aging might be linked to other health issues in infertile men. The researchers aim to find new biological markers that can help predict and prevent serious health problems, like tumors, in men who are struggling with infertility. By understanding these connections better, they hope to create personalized treatment plans to support men's health.
To be eligible for this trial, participants need to be men aged 18 to 50 who identify as White and have been diagnosed with certain types of infertility. They should be able to give their consent to participate. Men who have secondary infertility, a history of blood-related diseases, or have taken antibiotics in the last six months will not be able to participate. Those who join the study can expect to undergo tests that will help researchers gather important information about their health and infertility. It's a chance to contribute to valuable research that could lead to better understanding and treatment options for men facing infertility challenges.
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • Age \> 18 and \< 50 years;
- • White race
- • Men with OAT o iNOA infertility diagnosis
- • ability to sign the consent information
- Exclusion Criteria:
- • inability to sign the consent information
- • secondary infertility diagnosis
- • history of hematological diseases
- • people treated with antibiotics in the six months prior the enrollment
About Irccs San Raffaele
IRCCS San Raffaele is a prestigious research hospital and clinical trial sponsor based in Milan, Italy, renowned for its commitment to advancing medical science through innovative research and high-quality patient care. As an Institute for Research and Healthcare, it specializes in a wide range of therapeutic areas, including oncology, neurology, and cardiology, and is dedicated to translating scientific discoveries into effective clinical practices. With a multidisciplinary team of experts and state-of-the-art facilities, IRCCS San Raffaele plays a pivotal role in conducting rigorous clinical trials that contribute to the development of novel treatments and improve patient outcomes globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Milan, Lombardy, Italy
Patients applied
Trial Officials
Andrea Salonia, MD
Principal Investigator
IRCCS Ospedale San Raffaele
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported