Effect of Platelet-rich Plasma (PRP) Injection on Knee Osteoarthritis

Launched by XIJING HOSPITAL · Oct 9, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring the use of Platelet-rich Plasma (PRP) injections to help treat knee osteoarthritis, which is a common condition that causes pain and stiffness in the knees. The goal is to see how safe and effective these injections are in repairing damage to the knee joint and surrounding tissues. The study is currently looking for participants between the ages of 20 and 60 who have been diagnosed with knee osteoarthritis or have injuries to the cartilage or meniscus in the knee.

If you or someone you know is interested in participating, they will undergo some tests to ensure they meet the eligibility criteria and do not have any serious health issues that could affect the study. Participants can expect to receive PRP injections and will be monitored to evaluate the treatment's effects on their knee condition. It’s important to note that certain individuals, such as pregnant women or those with specific health issues, will not be eligible to join the study. This research aims to provide better treatment options for people suffering from knee injuries and osteoarthritis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The age range of the participants was 20 to 60 years old. Through a comprehensive clinical and imaging examination, it was conclusively determined that the individuals had knee osteoarthritis or experienced injuries to the cart, and meniscus surrounding the knee joint.
• • The preoperative routine tests and examinations revealed no contraindications.
• • Revised sentence: "Informed consent of the patient
• Exclusion Criteria:
• • The platelet count or function exhibits significant abnormalities、Systemic infection transmitted through the bloodstream.
• • Prolonged usage of anti-inflammatory drugs and systemic corticoid administration.
• • In injection site or damage to the skin.
• • Patients with tumors or undergoing radiotherapy and chemotherapy.
• • Pregnant or breastfeeding women.
• • Individuals with mental illnesses who are unable to cooperate with follow-up procedures.
• • Contraindications for MRI、Patients or their families do consent to participate in the study.
• • Other circumstances that render participation in the study unsuitable.