68Ga-TCR-FAPI PET/CT in Patients With Various Types of Cancer

Launched by CANCER INSTITUTE AND HOSPITAL, CHINESE ACADEMY OF MEDICAL SCIENCES · Oct 10, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging technique called 68Ga-TCR-FAPI PET/CT, which may help doctors see and assess suspected malignant tumors more clearly. The goal is to determine how effective this method is in patients who might have cancer, whether they are newly diagnosed or have had treatment in the past. The trial is currently recruiting participants aged 18 and older, and anyone who has signs of cancer supported by imaging tests or lab results may be eligible to join, as long as they are in relatively good health and can consent to participate.

If you participate in this trial, you can expect to undergo a PET/CT scan, which is a type of imaging test that helps doctors visualize your tumors. The study is designed to be open-label, meaning both you and the researchers will know what treatment you’re receiving. It's important to note that certain individuals may not be eligible, such as those with allergies to imaging agents or those who are pregnant or breastfeeding. Overall, this study aims to provide valuable information that could improve cancer diagnosis and treatment in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Suspected to have malignant tumors (supported by MRI and/or CT and/or tumor markers and/or pathology report), the tumor may be newly diagnosed or previously treated;
• • Meet the indications for PET examination, show a clear indication and no contraindications;
• • Have a performance status of score ≥ 80 on KPS scale or score 0-1 points on ECOG scale, a relatively good general situation;
• • No major organ dysfunction (heart, lung, liver, kidney and other major organ include), acute or life-threatening status of infection;
• • Be ≥ 18 years of age;
• • Be willing and able to understand the research content and provide written informed consent/assent for the trial.
• Exclusion Criteria:
• • Have a history of imaging agent allergies;
• • Does not meet the PET-CT scan sedation requirements, or has contraindications for PET-CT examination;
• • Be pregnant or breastfeeding, or expecting to conceive or father children within the projected duration of the trial.