Metabolic Responses to Exercise and Recovery

Launched by UNIVERSITY COLLEGE, LONDON · Oct 11, 2023

Keywords

ClinConnect Summary

This clinical trial, titled "Metabolic Responses to Exercise and Recovery," is exploring how exercise affects our bodies and how we recover afterward. The researchers want to find out the best levels of exercise for improving health, especially since this might change depending on a person's age and sex. To do this, they will study 48 healthy and active participants from three different age groups: children aged 8-10, young adults aged 23-27, and older adults aged 53-57.

To participate, individuals need to be healthy, active, and fit within certain weight guidelines. Participants will first fill out a questionnaire to see if they qualify, and if selected, they will spend about 4-5 hours in an exercise lab. During their visit, they will complete a treadmill exercise, and researchers will collect some samples (blood from adults and saliva from everyone) before the exercise, right after, and one hour later. This study is currently recruiting participants, so if you or someone you know fits the age and health criteria, this could be a great opportunity to contribute to understanding how exercise benefits our health!

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Aged 8-10, 23-27 or 53-57
• • 2. Considered healthy without a disease, disability or other condition that would impair participation in physical activity.
• • 3. Considered active.
• • 4. A body mass index within the ranges of 19 to 24.5 (adults) or the 2nd and 99th percentile (children)
• Exclusion Criteria:
• • 1. Outside required age brackets
• • 2. Having a disease, disability or other condition that would impair participation in physical activity.
• • 3. Having an implanted cardiac pacemaker, defibrillator, or other electronic medical devices.
• • 4. Receiving prescription medication one or more days every week over the past 3 months (some medications are permitted).
• • 5. Related by blood to another participant.
• • 6. Not willing at the time of recruitment to undergo blood sampling (adults only).
• • 7. Pregnancy/breastfeeding (adults only).
• • 8. Being a professional athlete.
• • 9. Not being physically active.
• • 10. Being a shift worker (night shift work for three or more days per week on more than two occasions in the six months before the visit day; adults only).
• • 11. Recent weight loss of more than 5% of weight in the last 6 months.
• • 12. Having a body mass index outside the range of 19 to 24.5 (adults) or outside the 2nd and 99th percentile (children)
• • 13. Smoking/vaping.
• • 14. Alcohol intake above a UK National Health Service (NHS) questionnaire cut-off.
• • 15. Regular use of recreational drugs.
• • 16. Not having reached menopause (for women aged 53-57 only).