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Search / Trial NCT06089850

Psychological Impact of Haploidentical Allogeneic Hematopoietic Stem Cell Transplantation on Donors

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Oct 17, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Hsc Transplantation Anxiety Depression Donors Hematology Familly Psychic State

ClinConnect Summary

This clinical trial is looking at the psychological effects of donating stem cells from family members in haploidentical transplants, a type of treatment for blood cancers. When patients need a stem cell transplant but can't find a fully compatible donor, they can turn to family members who share some genetic traits. This study aims to understand how this decision impacts the emotional well-being of donors, such as parents or children, and to see if they might need extra support during and after the donation process.

To participate in the trial, donors must be family members (either parents or children) who live in mainland France and are receiving care at certain medical centers. They should also understand and be able to communicate in French. The trial is currently recruiting participants, and those who join can expect to provide information about their feelings and experiences related to the donation process. This research is important because it will help doctors understand the emotional aspects of being a donor and guide them in providing appropriate support for those who choose to help their loved ones.

Gender

ALL

Eligibility criteria

  • Inclusion criteria:
  • Identical haplo CSH donors ascending (parents) or descending (children)
  • Major identical haplo HSC donors
  • Haplo-identical HSC donors living in mainland France and cared for in the centers participating in the study
  • Haplo-identical HSC donors benefiting from Social Security System.
  • Haplo-identical HSC donors who have signed the consent form
  • - Ability to read and write in French
  • Exclusion Criteria:
  • - Insufficient understanding of the French language

About Assistance Publique Hôpitaux De Paris

Assistance Publique - Hôpitaux de Paris (AP-HP) is a leading public hospital system in France, renowned for its commitment to healthcare excellence and innovative medical research. As a prominent clinical trial sponsor, AP-HP plays a pivotal role in advancing medical knowledge and improving patient care through rigorous scientific investigations across a wide range of therapeutic areas. With a focus on collaboration and interdisciplinary approaches, AP-HP leverages its extensive network of hospitals and expert clinicians to facilitate high-quality clinical trials that adhere to the highest ethical and regulatory standards, ultimately aiming to translate research findings into tangible health benefits for diverse patient populations.

Locations

Paris, , France

Patients applied

0 patients applied

Trial Officials

Eolia Brissot

Principal Investigator

Assistance Publique - Hôpitaux de Paris

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported