Effects of Sufentanil on the Intraoperative Hemodynamics

Launched by SEOUL NATIONAL UNIVERSITY HOSPITAL · Oct 13, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how two different medications, sufentanil and remifentanil, affect blood pressure during a specific type of surgery called extracranial-intracranial bypass surgery. The goal is to see if one medication helps keep blood pressure more stable than the other during the surgery. The study will include 92 patients who are scheduled for this procedure, and they will be randomly assigned to receive either sufentanil or remifentanil.

To participate in this trial, patients must be at least 18 years old and meet certain health criteria, such as having a mild to moderate health status (classified as grades 1, 2, or 3 by the American Society of Anesthesiologists). However, those with severe health issues, certain allergies, or specific medical conditions will not be eligible. Participants can expect to be closely monitored during their surgery to assess how well each medication works in maintaining stable blood pressure. This study is currently recruiting patients, and it aims to help improve care during surgeries by understanding which medication might be better for blood pressure control.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients who undergo elective extracranial-intracranial bypass surgery
• • American Society of Anesthesiologists grade 1,2,3
• • Age \> 18 years old
• Exclusion Criteria:
• • Refuse to participate to the study
• • American Society of Anesthesiologists grade 4
• • Body Mass Index \< 18.5 kg/m2 or \> 35 kg/m2
• • Allergic history of opioid
• • pregnant
• • MAO Inhibitor user
• • Severe respiratory insufficiency