Adipose Tissue Blood Flow in Aging Humans

Launched by MAYO CLINIC · Oct 19, 2023

Keywords

ClinConnect Summary

This clinical trial, titled "Adipose Tissue Blood Flow in Aging Humans," is looking to understand how blood flow in fat tissue changes as people age. Researchers want to find out if there are differences in blood flow in this tissue between younger adults (ages 18-35) and older adults (ages 65-80). They will also investigate what biological changes might be happening in the body that relate to these differences in blood flow.

To be eligible for the trial, participants should be healthy adults between 18-35 years or 65-80 years old with a body mass index (BMI) between 20 and 25. Those with certain health conditions, like diabetes or heart problems, or who are pregnant, nursing, or smokers, cannot participate. If you choose to join the study, you will have some tests done to measure blood flow in your fat tissue and provide small samples of fat tissue for analysis. You will also drink a sugary drink as part of the study. This research aims to help us learn more about how aging affects fat tissue and overall health.

Gender

ALL

Eligibility criteria

• • Inclusion criteria
• • Within the ages of 18-35 years or 65-80 years at time of study visit
• • BMI between 20-25.0 kg/m2.
• Exclusion criteria:
• • Presence of diagnosed cardiometabolic diseases (e.g., Type 2 diabetes, hypertension, Heart Failure)
• • Taking prescription anticoagulants
• • Taking prescriptions or supplements that effect adipose tissue metabolism (i.e., statins, Thiazolidinediones, niacin, atypical antipsychotics, or fish oil)
• • Pregnant or nursing
• • Inability to provide written informed consent
• • Smokers