Wrist Denervation Vs Exercise in Wrist Osteoarthritis

Launched by KAROLINSKA INSTITUTET · Oct 18, 2023

Keywords

ClinConnect Summary

This clinical trial is studying two different treatments for people with wrist osteoarthritis, a condition that causes pain and stiffness in the wrist due to the wear and tear of the joint over time. The trial compares a procedure called partial wrist denervation, which involves cutting certain nerves to reduce pain, with a self-managed exercise therapy program where participants will follow a set of exercises to improve their wrist function. The goal is to see which treatment works better for relieving pain and improving movement in the wrist.

To participate in this study, individuals must be at least 18 years old and have had chronic wrist pain for at least six months due to specific types of osteoarthritis. They will need to have certain signs of osteoarthritis confirmed through X-rays. However, people with certain conditions, previous surgeries on the wrist, or those who are currently undergoing other treatments for arthritis may not be eligible. Participants who join the trial will be randomly assigned to one of the two treatment groups and will be closely monitored throughout the study. This is an opportunity to explore new treatment options and contribute to research that could help others with similar conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 18 years.
• • Chronic wrist pain (≥6 months) due to Scapholunate advanced collapse (SLAC) / Scaphoid non-union advanced collapse (SNAC) grade 1-3 osteoarthritis.
• • Radiological signs of osteoarthritis on posteroanterior and lateral radiograph.
• Exclusion Criteria:
• • Previous PIN or AIN neurectomy.
• • Rheumatoid arthritis or other chronic inflammatory arthritis.
• • Symptomatic osteoarthritis in the distal radio-ulnar (DRU), Scapho-trapezio-trapezoid (STT) or thumb carpometacarpal (CMC) joints.
• • Ongoing infection.
• • Inability to co-operate with the follow-up protocol.
• • Systemic or intra-articular glucocorticoids or intraarticular PRP or Hyaluronic acid injections in the affected joint within 3 months prior to enrollment.