Developing a Nationwide Registry to Track Longitudinal Clinical Outcomes of Corneal Surgery and Disease

Launched by KERATOPLASTY ALLIANCE INTERNATIONAL · Oct 23, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on creating a nationwide registry to help track the long-term outcomes of corneal surgeries and diseases. The main goals are to collect important information about corneal transplant recipients, including details about the donor tissue, the surgery performed, and how patients do over time. By gathering this data, researchers hope to identify factors that lead to successful transplants and develop guidelines that can improve patient care. Additionally, they will collect and analyze images of the cornea using special technology to help create artificial intelligence tools for better diagnosing and predicting outcomes for corneal conditions.

If you have corneal disease or are planning to undergo corneal transplantation (like a type of surgery called penetrating keratoplasty or endothelial keratoplasty), you may be eligible to participate in this study. Participants will share their medical information, and imaging tests performed before surgery will be collected for analysis. The trial is currently seeking individuals aged 65 and older, regardless of gender. By joining this study, you’ll contribute to important research that could enhance the understanding and treatment of corneal diseases for patients in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * All subjects with corneal disease or undergoing corneal transplantation (either penetrating keratoplasty, endothelial keratoplasty \[including DSAEK and DMEK\], or anterior lamellar keratoplasty are eligible to be included in this study. Imaging studies performed pre-operatively, up until 1 year prior to surgery will be collected. Studies may include the following:
• • OCT
• • Corneal topography
• • Specular biomicroscopy
• • In vivo confocal biomicroscopy
• Exclusion Criteria:
• • Any criteria that does not meet the inclusion criteria above.