Correlation Patterns of Brain Temperature-Pressure in Acute Brain Injury

Launched by BEIJING TIANTAN HOSPITAL · Oct 24, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how brain temperature and pressure relate to each other in patients who have suffered acute brain injuries, such as a stroke or head trauma. The researchers want to understand if these patterns can help predict how well a patient will recover in the month following their injury. The study is currently recruiting participants aged 18 to 65 who have a moderate level of consciousness, as measured by a commonly used scale called the Glasgow Coma Scale.

To take part in the trial, participants need to have had a recent brain injury and must have a special device placed in their skull that measures both brain temperature and pressure continuously. Those who have more serious brain injuries or other significant health issues will not be eligible. If you or a loved one qualify and choose to participate, you can expect to contribute to important research that could improve understanding and treatment of brain injuries in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Adults, male or female, 18 to 65 years of age;
• • 2. Acute brain injury due to subarachnoid hemorrhage, cerebral hemorrhage, or craniocerebral trauma;
• • 3. Glasgow Coma Scale (GCS) score of 3-12;
• • 4. Have undergone intracranial pressure monitoring probe placement, which allows continuous recording of brain temperature and pressure data;
• • 5. Signed informed consent.
• Exclusion Criteria:
• • 1. GCS ≥13 points;
• • 2. Patients with concomitant intracranial infections, cerebral ischemia, congenital malformations, autoimmune encephalitis, or craniocerebral tumors;
• • 3. At the time of onset, there was a combination of systemic malignant tumor, acute stage of major systemic organ disease, or stage of functional decompensation;
• • 4. Maternity;
• • 5. Undergoing experimental drug or instrumental trials.