Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function (VCSIP) Longer Term Follow Up

Launched by OREGON HEALTH AND SCIENCE UNIVERSITY · Oct 27, 2023

Keywords

ClinConnect Summary

This clinical trial, called the VCSIP Longer Term Follow Up, is studying whether giving vitamin C to pregnant women who smoke can help improve their children's lung function by the time they are 10 years old. The researchers believe that vitamin C might help protect children from some of the negative effects of smoking during pregnancy. They want to see if children whose mothers took vitamin C during pregnancy have better breathing and lung health as they grow up compared to those whose mothers did not take vitamin C.

To be eligible for this study, women must have been part of the original VCSIP study, which included pregnant smokers who received either vitamin C or a placebo (a harmless sugar pill), as well as pregnant women who don’t smoke. Participants can expect regular follow-ups to assess their children's lung function over the years. This trial is important because it could provide valuable information on how prenatal nutrition, like vitamin C, may support better health outcomes for children exposed to smoking in the womb.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Women and their offspring randomized to vitamin C versus placebo during pregnancy as well as pregnant nonsmokers and their offspring enrolled as the reference group in the original VCSIP study
• Exclusion Criteria:
• • participants who specifically withdraw consent