International Post-Stroke Epilepsy Research Repository

Launched by YALE UNIVERSITY · Oct 24, 2023

Keywords

ClinConnect Summary

The cerebrovascular disease is the most common cause of late-onset epilepsy. PSE is associated with increased morbidity, including cognitive decline, dependence, and poor quality of life, and is a critical determinant factor of stroke prognosis. We recently reported a systematic review and meta-analysis of 71 papers that suggested that post-stroke seizures are associated with more significant mortality and poor functional and cognitive outcomes (PMID:37721736). In this study, we observed disparate methods used by the individual investigators. We also noted variations in study reporting. PI ...

Gender

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Eligibility criteria

• Inclusion Criteria:
• • Studies with minimum dataset of 100 patients
• • Studies comprising stroke patients aged ≥18 years, with ischemic or hemorrhagic stroke, presenting early or late PSS with data on patient outcome measures.
• • Documented consent or waiver of consent following local Institutional Review Board-approved procedure.
• • Studies published on human subjects.
• • No restriction based on the date or language of publication, gender, or ethnicity.
• Exclusion Criteria:
• • Studies of patients with a prior history of seizures before the index stroke,
• • Studies that did not report outcome data, or are not able to share IPD.