Intraoperative Oxygen Concentration on Incidence of Surgical Site Infection

Launched by ASSIUT UNIVERSITY · Oct 25, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how the amount of oxygen given to patients during surgery affects the chances of developing infections at the surgical site. Surgical site infections (SSIs) are common and can lead to serious health problems. The goal of the trial is to find out if adjusting the oxygen levels during surgery can help reduce these infections.

To participate in this study, you should be between the ages of 65 and 74, or 29 and 219, have a body mass index (BMI) of less than 35, and be scheduled for a planned surgery on your abdomen that will take longer than two hours. You should also be in good overall health, which means you would be classified as ASA I or II (a way doctors assess your physical health before surgery). If you have certain health issues, like uncontrolled diabetes or a recent fever, you may not be eligible. Participants can expect to receive careful monitoring throughout the study to ensure safety and collect important information about the effects of oxygen levels during their surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • - BMI of \<35 kg/m2
• • scheduled for elective abdominal laparotomy/ laparoscopy under general anesthesia with an expected surgical time longer than 2 h.
• • ASA I and II
• Exclusion Criteria:
• • - Patients undergoing minor procedures, where the expected duration of surgery will be less than 1 hour.
• • emergency surgeries for bowel obstruction.
• • abdominal surgery for vascular or plastic indications.
• • patients with a recent history of fever,
• • patients with uncontrolled diabetes mellitus,
• • patient with known immunological dysfunction (on steroids, decompensated liver disease, HIV, etc.).