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Search / Trial NCT06109480

Effect of HD-tDCS Assisted ECT for Depression Disorder

Launched by ANHUI MEDICAL UNIVERSITY · Oct 25, 2023

Trial Information

Current as of July 23, 2025

Recruiting

Keywords

Transcranial Direct Current Stimulation Electroconvulsive Therapy Depressive Disorder

ClinConnect Summary

This clinical trial is studying a new approach to help treat depression using a method called high-definition transcranial direct current stimulation (HD-tDCS) alongside traditional Electroconvulsive Therapy (ECT). The goal is to see if this combination can improve the effectiveness of ECT for people who are struggling with depression. The trial is currently looking for participants between the ages of 18 and 60 who have been diagnosed with depression by more than one psychiatrist and meet specific criteria for ECT treatment.

To be eligible, participants should have a certain level of education and be able to see well enough to complete various tests. However, individuals with serious medical conditions, other neurological diseases, certain mental disorders, or those who have had ECT in the past three months are not eligible. Participants can expect to receive care and support while contributing to important research that may lead to better depression treatments in the future. This trial is open to all genders and is an opportunity for those seeking help for their depression.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • the patients were diagnosed by more than 2 psychiatrists and met the diagnostic criteria of DSM-5 for depression, and HAMD\>17.
  • Meets the ECT treatment indication
  • the age ranged from 18 to 60 years old, and the length of education was more than 5 years.
  • the visual acuity or corrected visual acuity is normal, right-handed, can cooperate with the completion of various experimental tests.
  • Exclusion Criteria:
  • accompanied by severe somatic diseases, such as severe heart, liver, renal insufficiency and so on.
  • accompanied by other neurological diseases, such as stroke, epilepsy and so on. pregnant and lactating women.
  • accompanied by other mental disorders, such as drug abuse, schizophrenia, schizophrenic affective disorder, hysteria, autism and so on.
  • with a history of ECT treatment within the past 3 months

About Anhui Medical University

Anhui Medical University, a leading institution in medical education and research in China, is dedicated to advancing healthcare through innovative clinical trials and rigorous scientific inquiry. With a robust infrastructure and a commitment to ethical research practices, the university fosters collaboration among multidisciplinary teams to explore novel therapeutic interventions and improve patient outcomes. Its focus on translational medicine and public health reflects a deep commitment to addressing pressing health challenges both locally and globally. Through its clinical trial initiatives, Anhui Medical University aims to contribute significantly to the evidence base in medicine and enhance the quality of care provided to diverse populations.

Locations

Hefei, , China

Patients applied

0 patients applied

Trial Officials

Yanghua Tian, PhD

Study Chair

Anhui Medical University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported