Optimized Diagnosis and Precision Medicine of MODY

Launched by TAICHUNG VETERANS GENERAL HOSPITAL · Oct 26, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on understanding a specific type of diabetes called Maturity-Onset Diabetes of the Young (MODY) and how it differs from Type 2 Diabetes. Researchers want to gather detailed information about young people diagnosed with diabetes, including their family health history, medications, and genetic factors. They will look at how different types of MODY affect patients' health, how well they respond to diabetes medications, and the risk of complications. Participants will complete questionnaires and provide samples of blood and urine for testing, and they will be followed up regularly for several years to track their health.

To be eligible for this study, participants must have been diagnosed with diabetes at or before age 25 and have a body mass index (BMI) of 25 or lower, along with a family history of Type 2 diabetes. Close relatives of these participants can also join the study. The trial is open to all genders and is currently recruiting participants, so if you fit the criteria and are interested, you can reach out to learn more about joining. This study aims to improve our understanding of diabetes in young people and help tailor treatments to their specific needs.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Case Group Diagnosis of diabetes at or before 25 years of age. BMI (Body Mass Index) of 25 kg/m² or lower. Having at least one parent diagnosed with type 2 diabetes.
• • 2. Family Group Direct blood relatives of the case group, including brothers and sisters of the case group, who have contacted the research team through the subjects.
• • Expressing willingness to participate in this study after granting informed consent.
• • 3. Control Group Diagnosis of diabetes occurred at or before the age of 40, and the individual lacks typical MODY (Maturity-Onset Diabetes of the Young) characteristics.
• • At least one parent has been diagnosed with type 2 diabetes.
• Exclusion Criteria:
• • 1. Confirmed Diagnosed with type 1 diabetes.
• • 2. Under 18 years of age.
• • 3. Unable to personally provide informed consent.
• • 4. Patients with unrelieved leukemia.
• • 5. Patients who have undergone chemotherapy or radiation therapy for cancer within the last 12 months.
• • 6. Cases that have received a blood transfusion within the last six months.
• • 7. Unwilling or unable to continue treatment follow-up at this hospital.