Personalised Medicine in the Identification of Preclinical Cognitive Impairment. Development of a Predictive Risk Model
Launched by INSTITUTO DE SALUD CARLOS III · Oct 27, 2023
Trial Information
Current as of August 22, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how we can better predict early signs of cognitive impairment, which is a decline in thinking and memory skills, in people aged 55 to 70. Researchers want to collect and analyze a wide range of information about participants, including their medical history, lifestyle, and social factors, using advanced technology. The aim is to develop a model that helps identify individuals who might be at risk of cognitive issues before they become noticeable.
To be eligible for this study, participants need to be between 55 and 70 years old, living independently, and have no prior diagnosis of cognitive impairment. They should also have been connected to a primary care center in the study area within the last year. Participants will complete some questionnaires about their health and lifestyle, and they can expect to contribute to important research that could help identify cognitive issues sooner in the future. It's important to note that individuals with certain health conditions or those who are currently hospitalized may not be able to participate.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Non-institutionalised subjects from the study locations.
- • Aged between 55 and 70 years, attached to the PC centres of the territories included in the study
- • Living history (at least one record in the last 12 months)
- • Without an established diagnosis of CI.
- Exclusion Criteria:
- • Participants with significant difficulties in completing self-reported questionnaires
- • Those in whom genetic or biological testing may be affected by an underlying genetic or health condition.
- • Underlying genetic or health condition.
- • Patients who are hospitalised or institutionalised during follow-up will be excluded.
About Instituto De Salud Carlos Iii
Instituto de Salud Carlos III (ISCIII) is a prominent Spanish public research institution dedicated to advancing health through scientific investigation and innovation. As a key player in the national health system, ISCIII focuses on biomedical research, epidemiology, and public health, aiming to improve health outcomes and inform health policy. The institute fosters collaboration among researchers, healthcare professionals, and stakeholders, and it plays a pivotal role in funding and supporting clinical trials that contribute to the understanding and treatment of various diseases. Through its commitment to excellence and impact in health research, ISCIII is instrumental in shaping the future of healthcare in Spain and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Madrid, , Spain
San Vicente Del Raspeig, Alicante, Spain
Sant Boi De Llobregat, Barcelona, Spain
Albacete, Castilla La Mancha, Spain
Gibraleón, Huelva, Spain
Punta Umbría, Huelva, Spain
Bilbao, , Spain
Lleida, , Spain
Patients applied
Trial Officials
Angeles Almeida, PhD
Principal Investigator
Consejo Superior de Investigaciones Científicas (CSIC)
Rodrigo Barderas, PhD
Principal Investigator
Instituto de Salud Carlos III
MARIA TERESA MORENO-CASBAS, PhD
Principal Investigator
Nursing and Healthcare Research Unit (Investén-isciii). Instituto de Salud Carlos III. Madrid
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported