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Search / Trial NCT06114290

Personalised Medicine in the Identification of Preclinical Cognitive Impairment. Development of a Predictive Risk Model

Launched by INSTITUTO DE SALUD CARLOS III · Oct 27, 2023

Trial Information

Current as of August 22, 2025

Recruiting

Keywords

Cognitive Dysfunction Early Diagnosis Primary Health Care Biomarkers Artificial Intelligence Precision Medicine Care

ClinConnect Summary

This clinical trial is looking at how we can better predict early signs of cognitive impairment, which is a decline in thinking and memory skills, in people aged 55 to 70. Researchers want to collect and analyze a wide range of information about participants, including their medical history, lifestyle, and social factors, using advanced technology. The aim is to develop a model that helps identify individuals who might be at risk of cognitive issues before they become noticeable.

To be eligible for this study, participants need to be between 55 and 70 years old, living independently, and have no prior diagnosis of cognitive impairment. They should also have been connected to a primary care center in the study area within the last year. Participants will complete some questionnaires about their health and lifestyle, and they can expect to contribute to important research that could help identify cognitive issues sooner in the future. It's important to note that individuals with certain health conditions or those who are currently hospitalized may not be able to participate.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Non-institutionalised subjects from the study locations.
  • Aged between 55 and 70 years, attached to the PC centres of the territories included in the study
  • Living history (at least one record in the last 12 months)
  • Without an established diagnosis of CI.
  • Exclusion Criteria:
  • Participants with significant difficulties in completing self-reported questionnaires
  • Those in whom genetic or biological testing may be affected by an underlying genetic or health condition.
  • Underlying genetic or health condition.
  • Patients who are hospitalised or institutionalised during follow-up will be excluded.

About Instituto De Salud Carlos Iii

Instituto de Salud Carlos III (ISCIII) is a prominent Spanish public research institution dedicated to advancing health through scientific investigation and innovation. As a key player in the national health system, ISCIII focuses on biomedical research, epidemiology, and public health, aiming to improve health outcomes and inform health policy. The institute fosters collaboration among researchers, healthcare professionals, and stakeholders, and it plays a pivotal role in funding and supporting clinical trials that contribute to the understanding and treatment of various diseases. Through its commitment to excellence and impact in health research, ISCIII is instrumental in shaping the future of healthcare in Spain and beyond.

Locations

Madrid, , Spain

San Vicente Del Raspeig, Alicante, Spain

Sant Boi De Llobregat, Barcelona, Spain

Albacete, Castilla La Mancha, Spain

Gibraleón, Huelva, Spain

Punta Umbría, Huelva, Spain

Bilbao, , Spain

Lleida, , Spain

Patients applied

0 patients applied

Trial Officials

Angeles Almeida, PhD

Principal Investigator

Consejo Superior de Investigaciones Científicas (CSIC)

Rodrigo Barderas, PhD

Principal Investigator

Instituto de Salud Carlos III

MARIA TERESA MORENO-CASBAS, PhD

Principal Investigator

Nursing and Healthcare Research Unit (Investén-isciii). Instituto de Salud Carlos III. Madrid

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported