Effect of Mindfulness on Pain After Total Knee Arthroplasty

Launched by ROTHMAN INSTITUTE ORTHOPAEDICS · Oct 31, 2023

Keywords

ClinConnect Summary

This study is checking whether using the Headspace mindfulness app around the time of total knee replacement can help people do better after surgery. Specifically, researchers want to see if mindfulness training before and after the operation can lower pain after surgery, improve overall knee function and mood, and reduce the need for opioid pain medicines in people who also have depression or anxiety. Participants are randomly assigned to either have the knee replacement with Headspace or the knee replacement without Headspace, and the main checks happen about 6 weeks after surgery.

Who can join: adults (18+) having a first-time, unilateral total knee replacement and who have depression and/or anxiety that’s being treated (medication and/or psychotherapy) and who have a SF-12 Mental Health score below 45.6. You must own a smartphone to use Headspace and not currently be using a mindfulness app. Key exclusions include having both knees replaced at once or needing a revision surgery, and not having other mental health conditions beyond depression or anxiety. The study is being conducted at the Rothman Institute in Philadelphia, is randomized and open-label (no blinding), and plans to enroll about 140 participants. There are currently no results yet.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients undergoing unilateral primary TKA
• • AND
• • Patients with MDD who take medication for MDD and/or Patients with GAD who take medication for GAD
• • Patients with MDD and/or Patients with GAD who are being treated for those conditions with psychotherapy by a psychologist or psychiatrist
• • Patients with an SF-12 Mental Health Score less than 45.6
• • Owning a smartphone (Apple or Android) to be able to download the mindfulness application
• Exclusion Criteria:
• • Patients undergoing bilateral TKA
• • Patients undergoing revision TKA
• • Patients with mental health conditions other than MDD and/or GAD
• • Patients currently utilizing a mindfulness application