3D Printing to Improve Nasal Irrigation Outcome

Launched by OHIO STATE UNIVERSITY · Nov 1, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring how 3D printing can help people with chronic rhinosinusitis, a condition that causes long-lasting nasal congestion and sinus issues. The goal is to create a personalized 3D printed model of a patient's nose and sinuses. This model will be used to educate patients about their unique nasal anatomy, which may help them use nasal irrigation (a way to flush out the sinuses) more effectively. The researchers believe that by improving how patients irrigate their sinuses, they can enhance overall satisfaction and quality of life for those who are not candidates for surgery or prefer less invasive treatment options.

To be eligible for this trial, participants should have chronic rhinosinusitis either with or without nasal polyps, which are small growths in the nose. However, individuals with severe nasal polyps or certain other health conditions, like cystic fibrosis or pregnancy, will not be able to take part. If you join the study, you can expect to learn more about your nasal structure and how to manage your condition better using the 3D printed model, but you will not get any implants. The trial is currently recruiting participants of all genders, aged 18 and older.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Chronic rhinosinusitis without nasal polyps (CRSsNP) or Chronic rhinosinusitis with nasal polyps (CRSwNP).
• Exclusion Criteria:
• • Patients with significant nasal polyps (as determined by a clinician) were excluded upfront due to the unlikeness of irrigation penetration regardless of the head position. Patients with significant atopy, cystic fibrosis, granulomatosis with polyangiitis or other connective tissue disorder, and current pregnancy were also excluded.