Anesthetic Efficacy of 1.8 ml Versus 3.6 ml of 4% Articaine Buccal Infiltration
Launched by CAIRO UNIVERSITY · Nov 3, 2023
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is studying how effective different amounts of a local anesthetic called articaine are in numbing pain in patients with a specific dental condition known as symptomatic irreversible pulpitis. The researchers want to compare the effectiveness of two doses: 1.8 ml and 3.6 ml. They will look at how well each dose works and whether patients need any extra anesthesia during their dental treatment.
To participate in this study, patients should be generally healthy and fit into certain health categories defined by the American Society of Anesthesiologists. They need to be experiencing dental pain from irreversible pulpitis and be able to communicate their pain levels. However, individuals with allergies to the medications, pregnant or breastfeeding women, those who have taken pain medications recently, or those with more than one painful tooth in the same area won’t be eligible. If you join the study, you can expect to receive one of the two doses of articaine, and your pain relief will be monitored. This research could help improve dental care for patients dealing with similar issues in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Healthy patients who are categorized as I or II according to The American Society of Anesthesiologists (ASA class I or II).
- • 2. No sex predilection
- • 3. Patients with symptomatic irreversible pulpitis
- • 4. Patient with the ability to understand and use pain scales.
- • 5. Patients who accept to enroll in the study.
- Exclusion Criteria:
- • 1. Patients' allergies to any of the drugs or materials used in the study.
- • 2. Pregnant and lactating females.
- • 3. Patients taking analgesics in the last 6-8 hours.
- • 4. Patients having more than one symptomatic tooth in the same quadrant
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported