The Swedish BioFINDER - Primary Care Study

Launched by SKANE UNIVERSITY HOSPITAL · Nov 2, 2023

Keywords

ClinConnect Summary

The Swedish BioFINDER - Primary Care Study is a clinical trial designed to improve how doctors in primary care settings diagnose mild dementia and cognitive issues, including Alzheimer’s disease and other related conditions. The goal is to help doctors identify these problems earlier and more accurately so that patients can receive the right care and be referred to specialized memory clinics when needed. The study will involve developing new tests using simple blood tests, brain scans, and cognitive assessments that can be easily used in a primary care environment.

To participate in this study, you need to be at least 40 years old and experiencing cognitive symptoms, like memory problems, that concern either you or your doctor. However, if you have already been diagnosed with dementia, have certain health issues, or your cognitive problems are caused by a different condition, you may not be eligible. If you join, you can expect to undergo various tests to assess your cognitive health, and the findings may help improve how cognitive issues are managed in the future. This study is currently recruiting participants of all genders and backgrounds to ensure a diverse group.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. The patient seeks medical help because of cognitive symptoms experienced by the patient and/or informant OR The general practitioner suspects a progressive neurodegenerative disorder including, but not limited to, Alzheimer's disease, Lewy body disease, frontotemporal lobar degeneration or subcortical vascular cognitive impairment.
• • 2. The main symptom is usually memory complaints, but could also be executive, visuo-spatial, language, or attention complaints.
• • 3. Age ≥40 years
• • 4. Subjective cognitive decline, mild cognitive impairment or mild dementia
• Exclusion Criteria:
• • 1. Already diagnosed dementia
• • 2. Significant unstable systemic illness or organ failure that makes it difficult to participate.
• • 3. Current significant alcohol or substance misuse.
• • 4. Refusing investigation at the Memory clinic
• • 5. Cognitive impairment with acute onset due to stroke
• • 6. The cognitive impairment can with certainty be explained by another condition or disease such as significant anemia, infection, severe sleep deprivation, psychotic disorder, moderate-severe depression, alcohol abuse etc.