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Search / Trial NCT06120543

CYP1A2, ABCB1, CYP2C9 and Plasma Concentration of Agomelatine in Adult Patients With Depression

Launched by AFFILIATED HOSPITAL OF NANTONG UNIVERSITY · Nov 3, 2023

Trial Information

Current as of July 09, 2025

Not yet recruiting

Keywords

Gene Polymorphism Plasma Concentration Agomelatine Adult Depression

ClinConnect Summary

This clinical trial is studying how certain genetic factors in patients with depression affect the levels of a medication called agomelatine in their blood. Agomelatine is used to help improve mood and sleep. The researchers will look at specific genes (CYP1A2, ABCB1, and CYP2C9) that might influence how well the body processes this medication. By understanding these genetic differences, the goal is to create a personalized medication guide to help doctors prescribe agomelatine more effectively.

To be eligible for this trial, participants should be adults aged 18 to 75 who have been diagnosed with depression and also experience sleep problems. However, those with certain serious conditions, such as severe heart or liver issues, or other mental disorders, will not be able to join. Participants can expect to provide blood samples for testing and will help researchers learn more about how genetics can influence medication effectiveness. This trial is not yet recruiting, so there will be more details to come for interested individuals.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Clinical diagnosis of depression; Sleep disorder.
  • Exclusion Criteria:
  • Mental disorder; Intelligence disorder; Dementia; Aphasia; Dysarthria; Consciousness disorder; Severe heart, kidney or liver dysfunction; Pregnant and lactating women; Malignant tumor.

About Affiliated Hospital Of Nantong University

The Affiliated Hospital of Nantong University is a leading medical institution dedicated to advancing healthcare through innovative research and clinical excellence. As a prominent sponsor of clinical trials, the hospital is committed to enhancing patient care by conducting rigorous studies that align with ethical standards and regulatory requirements. With a strong emphasis on collaboration among multidisciplinary teams, the hospital leverages its state-of-the-art facilities and expert staff to foster groundbreaking research initiatives aimed at improving treatment outcomes and addressing critical health challenges.

Locations

Patients applied

0 patients applied

Trial Officials

Qin Wang

Study Director

Affiliated Hospital of Nantong University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported