Treatment of Hypopigmented Scars With Bimatoprost

Launched by MEDSTAR HEALTH RESEARCH INSTITUTE · Nov 2, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new treatment for hypo-pigmented scars, which are lighter areas of skin that can occur after a burn. In this study, participants who have two different hypo-pigmented scars will have one scar treated with a special medication called bimatoprost, while the other scar will receive a saline solution (a simple saltwater solution) as a comparison. Both scars will be treated using a laser technique over a period of 14 days, with follow-up visits to track how the treatment is working and to take small skin samples for further study.

To be eligible for this trial, participants must be at least 18 years old and have two hypo-pigmented scars that meet specific size and separation criteria. However, people with scars on their face or genital area, those who are allergic to the treatment, or women who are pregnant or breastfeeding cannot participate. Participants can expect to attend six treatment sessions over several weeks and will have regular check-ins to see how their scars are improving. This trial is currently recruiting participants of all genders, and it aims to find a better way to enhance skin color and appearance after injury.

Gender

ALL

Eligibility criteria

• • Inclusion Criteria
• • 1. Age ≥ 18 years
• • 2. Cutaneous trauma resulting in hypopigmented scar
• • 3. 2 different hypopigmented scars (at least 30cm2 each) with at least 2 inches of normal skin, hyperpigmented scar, or hypopigmented scar separating each hypopigmented study site scar
• • Exclusion Criteria
• • 1. Target hypopigmented scar to face or genitalia
• • 2. Known allergy to bimatoprost
• • 3. Known allergy to lidocaine
• • 4. Positive urine pregnancy test in women of childbearing potential (per point of care test)
• • 5. Lactating women (self-reported)
• • 6. Prisoner status