The Relationship Between NLR and PONV and ESPB

Launched by QIANFOSHAN HOSPITAL · Nov 9, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how a specific blood test result, called the Neutrophil-to-Lymphocyte Ratio (NLR), could help predict whether patients will experience nausea and vomiting after surgery, a condition known as PONV (Postoperative Nausea and Vomiting). The study also wants to see how a special type of pain relief technique, called the erector spinae plane block (ESPB), affects both NLR and PONV, as well as how it helps manage pain after spinal surgery and may reduce the need for strong pain medications.

To be eligible for this study, participants should be between 18 and 80 years old, and scheduled for elective lumbar spine surgery while lying face down under general anesthesia. They should be generally healthy, as indicated by a specific classification system. However, there are certain conditions that would exclude someone from participating, such as having uncontrolled health issues, prior surgeries on the spine, or being on certain medications. If you’re considering taking part in this study, you’ll need to sign an informed consent form, and you can expect to receive care as part of the trial that aims to improve your recovery experience after surgery.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients undergoing elective posterior lumbar spine surgery in a prone position under general anesthesia.
• • 2. ASA classification grades I to II.
• • 3. Age between 18 and 80 years old.
• • 4. Signed the informed consent for this study.
• Exclusion Criteria:
• • 1. Preoperative blood transfusion.
• • 2. Uncontrolled systemic diseases.
• • 3. Gastrointestinal system disorders.
• • 4. History of antiemetic and anticholinergic drug use.
• • 5. Adverse reactions related to surgery.
• • 6. Severe spinal deformities.
• • 7. Infection at the puncture site.
• • 8. Coagulation disorders.
• • 9. Long-term use of sedatives and analgesic drugs before surgery.
• • 10. Patients with mental illness or communication barriers.
• • 11. Allergic to ropivacaine.
• • 12. Participants involved in other clinical studies within the past 3 months.
• • 13. History of previous lumbar surgeries.
• • 14. Subjective unwillingness to participate in this study.