Hyperbaric Oxygen Therapy for Optic Neuropathies

Launched by STANFORD UNIVERSITY · Nov 7, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at the use of hyperbaric oxygen therapy to help protect the nerves in patients who have optic neuropathy, a condition that can affect vision, and glaucoma, a disease that damages the eye’s optic nerve. The hope is that breathing oxygen in a pressurized environment may improve or stabilize vision in those affected. The study is currently recruiting participants aged 18 and older who have been diagnosed with optic neuropathy and can follow the study's requirements.

To be part of this trial, participants must be able to understand and sign consent forms, even if they need assistance due to vision issues. However, individuals with certain conditions, such as severe visual impairments, those who have participated in other recent clinical trials, or pregnant individuals, are not eligible. Participants will undergo specific procedures and check-ups during the study, and their experiences will be closely monitored. This research could provide new insights into treating optic neuropathies and improving quality of life for those affected.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• * Patients must meet all of the following criteria to join the study (all eligibility criteria must be met at the screening and baseline visits unless otherwise noted):
• • Participant must be at least 18.
• • Participant must has the ability to comply with the requirements of the study and complete the schedule of events (SOE).
• • Participant's with clinical evidence of optic neuropathy.
• • Participant must understand and sign the informed consent. If the participant's vision is impaired to the point where he/she cannot read the informed consent document, the document will be read to the participant in its entirety.
• Exclusion Criteria:
• • Participant is unable to comply with study procedures or follow-up visits.
• • Participant has evidence of corneal opacification or lack of optical clarity.
• • Participant is currently participating in or has within the last 3 months participated in any other clinical trial of a drug by ocular (if in the study eye) or systemic administration.
• • Participant is pregnant or lactating.
• • Participant has, in the opinion of the investigator, any physical or mental condition that would increase the risk of participation in the study or may interfere with the study procedures, evaluations and outcome assessments.
• • Children and comatose patients.
• • Participant abusing drugs or alcohol.
• • Prior treatment with hyperbaric oxygen within the last 6 months.
• • Participant with claustrophobia or that cannot decompress properly.