Clinical Efficacy and Safety of Dexmedetomidine as an Adjuvant in Quadratus Lumborum Versus Epidural Block in Postoperative Patients

Launched by ASSIUT UNIVERSITY · Nov 10, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the effectiveness and safety of a medication called dexmedetomidine when used alongside a specific type of pain relief technique known as the quadratus lumborum block, compared to the traditional epidural block. This research focuses on patients who have undergone major surgery on their lower abdomen, particularly for cancer. The goal is to see if using dexmedetomidine can help manage pain better after surgery.

To be eligible for this trial, participants should be between 18 and 70 years old and must be in generally good health (with mild physical status). They should be having major lower abdominal surgery. However, patients with certain conditions like bleeding disorders, those dependent on opioids, or anyone with infections or allergies to the medications involved will not be able to participate. If someone joins the trial, they can expect to receive either the dexmedetomidine with the quadratus lumborum block or the epidural block to help with pain after their surgery, contributing to important research in pain management.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. patient's 18-70years old
• • 2. ASA I-II and NYHA I-II.
• • 3. type of surgery: major lower abdominal cancer surgery
• Exclusion Criteria:
• • 1. Patients who refused to participate in the study.
• • 2. coagulation disorders.
• • 3. opioid dependence.
• • 4. sepsis or local infection at or near the vicinity of the block site.
• • 5. patients with psychiatric illnesses that would interfere with perception and assessment of pain.
• • 6. allergy to any of the studied drugs.