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Search / Trial NCT06132516

Effects of HIIT on HRV in Sub-acute Post-stroke Patients

Launched by HÔPITAL LÉON BÉRARD · Nov 9, 2023

Trial Information

Current as of August 19, 2025

Not yet recruiting

Keywords

Acute Post Stroke Phase Rehabilitation Hiit Heart Rate Variability

ClinConnect Summary

This clinical trial is studying how "High-Intensity Interval Training" (HIIT) can affect heart health after a stroke. Specifically, researchers want to see if this type of exercise can improve Heart Rate Variability (HRV), which is an important measure of how well a person’s heart is functioning after a stroke. The trial will involve patients who have had their first stroke within the last three months and who have certain medical conditions that make them eligible.

If you or someone you know has experienced a stroke and meets the criteria, you may have the chance to participate in this study. Participants will be divided into two groups: one will take part in traditional rehabilitation exercises along with HIIT sessions, while the other group will do gentler gymnastic exercises. Over six weeks, participants will have a total of 16 sessions. The researchers will monitor heart health using a special heart monitor during the study. This trial aims to find out if incorporating HIIT can lead to better outcomes for stroke patients during their recovery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • first-ever hemispheric stroke, with consistent clinical and neuroimaging signs
  • \<3 month
  • NIHSS \<20 in acute care
  • Exclusion Criteria:
  • age\<18 years-old
  • * diabetes mellitus complicated by neuropathy or autonomic dysfunction; or any other concomitant nervous system, cardiac or pulmonary disease possibly affecting the autonomic nervous system ie:
  • myocardial infarction\< 6 months,
  • myocardial dysfunction as severe dilated or hypertrophic cardiomyopathy, class 3 and 4 heart failure,
  • severe conduction abnormalities and arrhythmias, including chronic atrial fibrillation,
  • mechanical ventilation,
  • beta-blockers with no alternative options, pharmacological mandatory treatment possibly affecting the autonomic nervous system and HRV.
  • severe cognitive impairment inconsistent with free, informed and written consent or questionnaire filling

About Hôpital Léon Bérard

Hôpital Léon Bérard is a leading specialized cancer center located in Lyon, France, dedicated to advancing cancer research and improving patient care. As a prominent clinical trial sponsor, the institution focuses on innovative therapeutic approaches and cutting-edge treatments, encompassing a wide range of oncological disciplines. Hôpital Léon Bérard collaborates with a network of national and international partners to facilitate groundbreaking studies, aiming to enhance treatment efficacy and patient outcomes. With a commitment to excellence in patient-centered research, the hospital plays a pivotal role in shaping the future of oncology.

Locations

Patients applied

0 patients applied

Trial Officials

Olivier Gavarry

Study Chair

Toulon University, STAPS Faculty

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported