Adherence, Viability, Clinical Evolution and Therapeutic Efficacy in Patients Undergoing Bone Marrow Transplantation

Launched by FEDERAL UNIVERSITY OF HEALTH SCIENCE OF PORTO ALEGRE · Nov 10, 2023

Keywords

ClinConnect Summary

This is a randomized clinical trial. Patients will be allocated into groups (1) Aerobic; (2) Anaerobic and (3) Mixed. The manifestation of signs and symptoms will be evaluated using the Edmonton Symptom Assessment System (ESAS) inventory, a sensation of fatigue using the multidimensional fatigue questionnaire (MIF), and quality of life using the European Organization for Research and Treatment of Cancer Core Quality of Life questionnaire. Questionnaire (EORTC QLQ-30) and the incidence and intensity of anxiety and depression symptoms using the General Hospital Anxiety and Depression Scale (H...

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • Be between 18 and 64 years old;
• • Present hematological malignancy undergoing first antineoplastic treatment with HSCT;
• • Have intact neurological function and cognition;
• • Be in clinical conditions that allow participation in physical rehabilitation;
• • To agree with the study proposal by signing the Free and Informed Consent Form (TCLE).
• Exclusion criteria:
• • Present clinical complications that impair the performance of motor physiotherapy, including the practice of cycle ergometer and resistance exercises;
• • Present previous musculoskeletal changes that interfere with the execution of physical performance assessment tests;
• • Patients with limiting cardiovascular or pulmonary disease, significant psychiatric or neurological disorders and/or limiting interpretation of documents and forms that will be used in the study;
• • Patients who require mobility assistance and/or diagnosed with multiple myeloma with or without the presence of bone metastasis;