Electroporation for Treatment of Atrial Fibrillation

Launched by UNIVERSITY MEDICAL CENTRE LJUBLJANA · Nov 13, 2023

Keywords

ClinConnect Summary

Patients with persistent and longstanding persistent atrial fibrillation will be randomized to control and investigational group.

In control group they will receive pulmonary vein and posterior wall ("box lesion") isolation with point by point radiofrequency ablation utilizing the CLOSE protocol with predetermined interlesion distance of up to 6 mm and predetermined ablation index/lesion size index.

In investigational group they will receive pulmonary vein and posterior wall ("box lesion" and additional ablations inside the "box") isolation with point by point pulse field ablation with a ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • atrial fibrillation recorded with 12-lead ECG, holter ECG or implantable device on two occasions at least one week apart
• Exclusion Criteria:
• • history of previous catheter ablation, history of previous heart surgery, life expectancy less than one year, any lifethreatening severe acute condition, acute deep venous thrombosis, presence of intracardiac masses or thrombi.