Role of Senescent Cells in Uterine Fibroid Pathogenesis (SOUL Study)

Launched by JOHNS HOPKINS UNIVERSITY · Nov 13, 2023

Keywords

ClinConnect Summary

The SOUL Study is a clinical trial that is looking into a specific type of cell called senescent cells to understand their role in the development of uterine fibroids, which are non-cancerous growths in the uterus. The trial is currently recruiting women aged 18 to 55 who may have fibroids and have been sexually active or have undergone a vaginal exam. Participants should be able to read and understand either English or Spanish to ensure they can fully grasp the study's procedures and consent information.

If you decide to join this trial, you will be asked to complete some questionnaires and may undergo certain tests related to your fibroids. It's important to note that women who are pregnant, have uterine cancer, or are unwilling to sign consent forms are not eligible to participate. This study aims to gather valuable information that could lead to better understanding and treatment of uterine fibroids in the future.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Subjects must be women above the age of ≥18 - ≤55 years.
• • Women with suspected uterine fibroids.
• • Subject must be or have been sexually active or have had a previous vaginal exam that used a speculum.
• • Subject must be able to understand, read and speak English or Spanish and subsequently, be able to understand what she is consenting to in terms of procedures and use/disclosure of protected health information.
• Exclusion Criteria:
• • Unwilling to sign the consent form or complete questionnaire.
• • Pregnancy.
• • Cancer of the uterus