ClinConnect ClinConnect Logo
Search / Trial NCT06138964

Comparing the Effect of siSPARC Microneedle Patch Versus siSPARC+siLR4A Microneedle Patch on Post-surgical Scars

Launched by NATIONAL SKIN CENTRE · Nov 17, 2023

Trial Information

Current as of July 22, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying two different types of patches that are applied to post-surgical scars to see which one helps improve their appearance better. One patch, called siSPARC, contains tiny needles that deliver a special treatment designed to help heal the skin. The other patch combines siSPARC with an additional treatment called siLR4A. Researchers want to find out if using the combined patch gives better results than using siSPARC alone.

To participate in this trial, you need to be an adult between the ages of 21 and 75 who has had surgery with stitches removed within the last two weeks. Your wound should be healed properly, and you should not be pregnant, have an infection, or have any allergies to the patch's ingredients. If you choose to join, you will apply one of the patches daily for a set period. This study is currently recruiting participants, and it aims to improve treatments for scars, which can be important for both appearance and confidence after surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adult
  • Age 21-75
  • 2 weeks (+/- 7 days) after surgical operation with incision into the dermis
  • Post-stitch removal when stitches were applied
  • Wound closure/union achieved
  • Exclusion Criteria:
  • Pregnant or lactating participant
  • Participants with wound infection
  • Participants assessed to be uncooperative or unable to self-administer the interventions
  • Participants with known contact allergy to ingredients in the patch formulation (comprising hyaluronic acid, siRNA and glue) and/or isopropyl alcohol
  • Participants who are unable to personally consent (for e.g., cognitively impaired)

About National Skin Centre

The National Skin Centre (NSC) is a premier clinical research institution dedicated to advancing dermatological care through innovative research and clinical trials. As a leading sponsor of cutting-edge studies, NSC focuses on the evaluation of new treatments and therapies for a wide range of skin conditions, with a commitment to improving patient outcomes and enhancing the understanding of dermatological health. Leveraging a multidisciplinary team of experts and state-of-the-art facilities, the National Skin Centre strives to contribute to the global body of dermatological knowledge, ensuring that patients benefit from the latest advancements in skin health.

Locations

Singapore, , Singapore

Patients applied

0 patients applied

Trial Officials

Hong Liang Tey

Principal Investigator

National Skin Centre

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported