Changes in Hemorrhage With Prophylactic Oxytocin for Dilation and Evacuation

Launched by UNIVERSITY OF COLORADO, DENVER · Nov 15, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the use of a medication called oxytocin to see if it can help reduce bleeding during a medical procedure known as dilation and evacuation (D&E), which is often done in the second trimester of pregnancy. The trial is currently looking for women aged 18 and older who will be having a D&E at 18 weeks of pregnancy or more, and who can speak either English or Spanish. However, some women may not be eligible to participate if they have certain medical conditions or have recently taken specific medications that affect blood clotting.

Participants in this trial can expect to receive oxytocin before their procedure and will be monitored for any changes in bleeding. This study aims to gather important information that could help improve safety and care for women undergoing this type of procedure in the future. If you're interested in joining the trial or learning more, please talk to your healthcare provider for more details.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • clinic-based D\&E at 18 weeks gestational age and above
• • speaks English or Spanish
• Exclusion Criteria:
• • refuses IV
• • history of coagulopathy
• • anticoagulant use in the preceding five days
• • chorioamnionitis or sepsis
• • suspected placenta accreta spectrum
• • intrauterine fetal demise
• • multiple gestation
• • use of misoprostol for cervical preparation