Study to Investigate an Association Between Brain Activity and Tidal Volume in Humans (BATMAN)

Launched by UNIVERSITY HEALTH NETWORK, TORONTO · Nov 15, 2023

Keywords

ClinConnect Summary

The BATMAN study is looking into how breathing, especially when using machines to help with ventilation, is connected to brain activity in humans. Researchers want to understand if the amount of air delivered to the lungs affects brain function and whether this could lead to brain cell damage. This is particularly important for very ill patients who rely on breathing machines, as they may face risks of cognitive problems if the connection between their breathing and brain activity isn't well understood.

To participate in this study, you should be at least 18 years old and scheduled for an MRI scan of your head under general anesthesia. However, if you have had a stroke or brain tumor, a history of dementia, brain surgery, or certain nerve injuries, you may not be eligible. If you join the study, you'll help researchers learn more about how breathing machines might impact brain health, which could lead to better care for patients needing breathing support in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Patients scheduled to undergo an MRI scan of their head under general anesthesia
• • 2. Age \> 18 years
• Exclusion Criteria:
• • 1. Stroke, and/or brain tumor in the regions of interest that has not been diagnosed before the MRI scan
• • 2. Previous medical history of dementia
• • 3. Previous medical history of brain surgery
• • 4. Acute or chronic spinal cord Injury
• • 5. Previous Vagotomy
• • 6. Phrenic nerve injury