A Analgesic Study of Adductor Canal &IPACK Block with Liposomal Bupivacaine in Knee Arthroplasty

Launched by NANJING FIRST HOSPITAL, NANJING MEDICAL UNIVERSITY · Nov 20, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a combination of two pain management techniques, called Adductor Canal Block (ACB) and iPACK block, along with a special medication called liposomal bupivacaine. The goal is to see how effective these methods are in helping patients manage pain after undergoing knee replacement surgery, which is also known as knee arthroplasty. If you or a loved one are aged between 18 and 79 and are planning to have a knee replacement, you may be eligible to participate in this study.

Participants in the trial can expect to receive the pain management techniques and the medication during their surgery. The researchers are looking for individuals who are generally healthy, without serious medical conditions, and who do not have any major issues that could complicate the surgery or recovery. This study is currently recruiting participants, and it offers an opportunity to help improve pain management for future knee surgery patients. If you’re considering joining, it’s a chance to contribute to important research while potentially benefiting from enhanced pain relief after your procedure.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Age 18-79 years.
• • 2. Patients undergoing unilateral total knee arthroplasty or unicondylar joint replacement.
• • 3. Normal diet.
• • 4. ASA grade I\~Ⅲ;
• • 5. BMI 18-30kg /m2.
• • 6. No intraspinal anesthesia contraindications.
• Exclusion Criteria:
• • 1. Patients with severe neurological diseases.
• • 2. Hearing and speech impaired.
• • 3. Preoperative gastric emptying disorders, such as gastrointestinal obstruction, gastroesophageal reflux, or previous gastrointestinal surgery, etc.
• • 4. Patients with severe renal insufficiency or other severe metabolic diseases.
• • 5. Mental disorders, alcoholism or a history of drug abuse.
• • 6. The surgical time is greater than 3 hours.
• • 7. Puncture site infection, abnormal coagulation function, and local anesthetic allergy.