Effects of Individualized iTBS on Upper Limb Function After Stroke

Launched by QILU HOSPITAL OF SHANDONG UNIVERSITY · Nov 19, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called individualized intermittent theta burst stimulation (iTBS) to see if it can improve upper limb function in people who have had a stroke. The goal is to find out if this personalized approach is better than the standard iTBS treatment. The researchers want to know not only if the treatment helps patients move their arms and hands better but also if these improvements last over time. They will use a special technique called functional near-infrared spectroscopy (fNIRS) to understand how the treatment works in the brain.

To be eligible for the trial, participants must be aged 18 to 80, have had their first stroke within the last 1 to 3 months, and experience some difficulty using their arms. They also need to be able to understand the study and agree to participate by signing a consent form. Participants will go through some tests before starting the treatment and will be randomly assigned to one of three groups: one receiving individualized iTBS, another getting standard iTBS, and a third group receiving a placebo treatment that doesn’t have any active ingredients. Throughout the study, participants will have follow-up assessments to monitor their progress. This trial is not yet recruiting participants, but it aims to provide valuable information on how best to help stroke survivors regain upper limb function.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. aging from 18-80
• • 2. diagnosed as first-happened stroke,duration of the disease ranged from 1-3 months
• • 3. upper extremity impairment
• • 4. with mini-mental state examination\>15
• • 5. agree to participate in this study and sigh the informed consent
• Exclusion Criteria:
• • 1. with stroke history
• • 2. have metal device within the body
• • 3. with history of upper extremity trauma,fracture, and/or burn
• • 4. serious conditions and can not finish the examination and treatment