Mobile Internet Healthcare and Three Disciplines Co-management Intervention for Overweight/Obese Prediabetic Patients

Launched by THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY · Nov 22, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to help overweight or obese patients who are at risk of developing diabetes, known as prediabetes. The study is testing a program that uses mobile internet technology to support patients in managing their weight and health. Participants will be divided into two groups: one will receive standard care from doctors and dietitians, while the other will get a more comprehensive approach that includes a team of specialists working together to provide personalized support for their diet, exercise, and weight management. The goal is to see if this new approach can help improve their weight, blood sugar levels, and overall health more effectively than traditional methods over a six-month period.

To join the trial, participants must be between 18 and 70 years old, have specific blood sugar levels indicating they are prediabetic, and have a body mass index (BMI) between 24 and 45. However, people with diagnosed diabetes, certain health conditions, or who have recently taken certain medications may not be eligible. Participants can expect regular check-ins and guidance on their diet and exercise routines, helping them to achieve better health outcomes. This study is important because it aims to find effective ways to prevent diabetes, which can lead to serious health problems.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • ①18 years≤ Age\<70 years
• • 5.7mmol/L≤ fasting blood glucose \<6.9mmol/L
• • 7.8mmol/L≤2h blood glucose \<11.0mmol/L;
• • 24Kg/m2≤BMI≤45Kg/m2
• Exclusion Criteria:
• • Diagnosed diabetes
• • In the past 3 months, metformin, thiazolidinedione, acarbose and weight reduction drugs were used
• • Severe infection, severe trauma or other stress
• • The weight fluctuation in the past 3 months was \>5%
• • Aspartate Transaminase(AST) or Alanine Aminotransferase（ALT） increased the upper limit of 3 times the normal value; Creatinine greater than 1.5 times the upper limit of normal; Estimated Glomerular Filtration Rate（eGFR） 30 ml/min / 1.73 m2 or less
• • Serious cardiovascular and cerebrovascular disease in the past 6 months
• • Abnormal thyroid function not controlled;
• • Pregnant and breastfeeding women