Magnesium Sulphate in Oblique Subcostal TAP Block

Launched by ASSIUT UNIVERSITY · Nov 27, 2023

Keywords

ClinConnect Summary

This clinical trial is studying whether adding magnesium sulfate (MgSO4) to a pain relief method called an oblique subcostal transversus abdominis plane (TAP) block can help manage pain better after laparoscopic cholecystectomy (LC), which is a surgery to remove the gallbladder. The researchers want to see how different doses of magnesium sulfate mixed with a common pain medication, bupivacaine, affect pain control in patients for up to 24 hours after the surgery.

To participate in this study, you need to be between 18 and 60 years old and scheduled for elective gallbladder surgery. You should be in good health (classified as ASA physical state I or II) and able to communicate your pain levels after surgery. However, if you have certain health issues, like severe obesity, chronic pain, or problems with your kidneys, liver, or heart, you won't be eligible. This trial is not currently recruiting participants, so there will be more information released as it gets closer to starting.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • • Patients programmed for elective LC.
• • American society of anesthesiologists (ASA) physical state I or II.
• • Age over 18 years and less than 60 years old.
• • Patients of both sex are included in the study.
• Exclusion Criteria:
• • • Patient refusal.
• • Known hypersensitivity to the study drugs.
• • Body Mass Index \> 40 kg/m2.
• • Inability to accurately describe postoperative pain to investigators.
• • Opioid tolerance or dependence.
• • Preexisting history of chronic pain.
• • History of renal, liver, cardiac, neuropsychiatric disorder problems.
• • Bleeding or coagulation abnormality.