Intervention Effect of High-Definition Transcranial Direct Current Stimulation (HD-tDCS) on Non-suicidal Self-injury (NSSI)

Launched by ANHUI MEDICAL UNIVERSITY · Nov 19, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a treatment called high-definition transcranial direct current stimulation (HD-tDCS) to help patients who engage in non-suicidal self-injury (NSSI). NSSI means hurting oneself without wanting to end one’s life. The researchers want to see how effective this treatment is and understand how it works in the brain using brain scans (MRI).

To participate in the trial, patients need to be between 12 and 18 years old and have been diagnosed with NSSI by two or more doctors. They must not have made any recent changes to their medications and should not have thoughts or behaviors related to suicide. Participants will receive the HD-tDCS treatment and may undergo brain scans during the study. It’s important to know that individuals with certain medical conditions, previous brain injuries, or specific types of medical devices may not be eligible for this trial. Overall, this study aims to find new ways to support young people struggling with self-injury.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • The patients were diagnosed by 2 or more senior clinical psychiatrists, meeting DSM-V criteria, and having 1 or more non-suicidal self-injurious behaviors in the last 6 months.
• • 12-18 years of age.
• • The medicine has not changed in the 4 weeks prior to or after this study, and if it has to be changed, the treatment medication is required to be at a subtherapeutic dosage level.
• Exclusion Criteria:
• • The patient has suicidal ideation or has committed suicidal behavior
• • T1 or T2 weighted phase magnetic resonance images show focal brain lesions
• • patients had neurological disorders such as epilepsy, or serious physical illnesses
• • patients had a history of substance abuse and drug dependence in the last 6 months or use of anticonvulsant drugs in the last 3 months
• • patients had received radial cranial electrical stimulation or magnetic stimulation treatment in the last 3 months or received electroconvulsive therapy in the last 6 months
• • patients had previous significant head trauma or EEG abnormality in the last 1 month
• • body-mounted devices unsuitable for treatment, such as pacemakers, artificial valves, and other metal implants.