Fractionated 1927-nm Non Ablative Thulium Laser in Treating Post Inflammatory Hyperpigmentation

Launched by HENRY FORD HEALTH SYSTEM · Nov 20, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a special type of laser treatment called the fractionated 1927-nm non-ablative thulium laser to see if it can help reduce dark patches on the skin known as post-inflammatory hyperpigmentation (PIH). This condition often occurs after skin inflammation or injury, and the trial aims to find out if three monthly sessions of this laser treatment can make a difference. Additionally, researchers will look at how effective a topical ointment, clobetasol propionate, is when used after the laser treatment and will examine any changes in the skin at a cellular level.

To participate in the trial, you need to be at least 18 years old and have specific skin types (IV to VI). It's important that you can understand the study and its risks, and you must be able to sign a consent form. Before starting the treatment, participants should stop using any medications for skin pigmentation for a month, except for sunscreen. If you have any skin issues like birthmarks or tattoos on the treatment area, or if you are pregnant or breastfeeding, you won't be eligible for this study. Participants can expect to receive the laser treatment and potentially the ointment while helping researchers learn more about how these treatments can improve skin conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient age 18 and older
• • Patient with skin phototypes IV-VI
• • Patient able to understand requirements of the study and risks involved
• • Patient able to sign a consent form
• • Patient to have discontinued all oral medications used to treat pigmentary abnormalities and all topical medications, except for sunscreen, used to treat pigmentary abnormalities on the buttocks one month prior to treatment
• Exclusion Criteria:
• • A patient who has skin dyspigmentation, birth marks, tattoos, or other skin findings at baseline on either buttock that may obscure study results
• • A patient who is lactating, pregnant, or planning to become pregnant