Pilot Study Evaluating the Elasticity and Shear Wave Modulus (Stiffness) of the Median Nerve in Patients With Mild to Moderate Idiopathic Carpal Tunnel Syndrome Receiving OMT and Conservative Therapy

Launched by KETTERING HEALTH NETWORK · Nov 20, 2023

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ClinConnect Summary

This clinical trial is studying how flexible and stiff the median nerve becomes in patients with mild to moderate carpal tunnel syndrome after they receive a specific type of therapy called osteopathic manipulative therapy (OMT) along with standard care. Carpal tunnel syndrome can cause pain, numbness, and weakness in the hand due to pressure on the median nerve, which runs through the wrist. Researchers want to see if OMT can help improve the condition by measuring changes in the nerve's elasticity and stiffness.

To participate in the trial, individuals must have a diagnosis of mild to moderate carpal tunnel syndrome, confirmed by recent tests. However, people with certain conditions, such as severe carpal tunnel syndrome, recent wrist injuries or surgeries, or certain systemic diseases (like diabetes or thyroid disorders), are not eligible. Participants in the study will likely undergo assessments to measure the stiffness of their median nerve and receive OMT treatment. This trial is currently looking for volunteers of all genders between the ages of 18 and 74 who meet the eligibility criteria. If you're considering joining, it’s a great opportunity to contribute to understanding potential treatments for carpal tunnel syndrome.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of unilateral or bilateral mild to moderate carpal tunnel syndrome, based on recent EMG findings
• Exclusion Criteria:
• • History of undergoing recent physical therapy for treatment of carpal tunnel syndrome
• • History of wrist trauma or surgery
• • Hypothyroidism
• • Severe CTS that has progressed to muscle atrophy
• • Systemic disease or condition including but not limited to diabetes mellitus, thyroid disorders, rheumatoid disorders, Paget's bone disease, gout, myxedema, multiple myeloma, acromegaly, hepatic disease, dialysis patients, or other diseases or conditions in which peripheral neuropathies are common.
• • Secondary cause of CTS such as a ganglion cyst, mass, or an accessory muscle shown by US or MRI of the affected wrist.
• • Bifid median nerve as shown by US or MRI of the affected wrist
• • pregnant or recently postpartum