Evaluation of the Role of Poisoning Severity Score, Serum Procalcitonin and C-reactive Protein in Acute Hydrocarbon Intoxicated Cases Admitted to the Poison Control Center Ain Shams University Hospitals

Launched by SOHAG UNIVERSITY · Nov 21, 2023

Keywords

ClinConnect Summary

This clinical trial aims to study the effects of acute hydrocarbon poisoning—poisoning caused by common substances like fuels, solvents, and cleaning products—on patients. Researchers want to learn how certain blood tests, called the Poisoning Severity Score, Serum Procalcitonin, and C-reactive Protein, can help assess the seriousness of this type of poisoning. Hydrocarbons can be very dangerous, especially when inhaled or ingested, so understanding their impact is crucial.

To participate in this trial, individuals must be admitted to the Poison Control Center at Ain Shams University Hospitals within 24 hours of experiencing acute hydrocarbon poisoning. This study will include both men and women, but some people will not qualify, such as those who have been treated before arriving at the hospital, pregnant women, or individuals with certain health conditions like severe infections or heart problems. If eligible, participants can expect to undergo assessments related to their poisoning and contribute to important research that could help improve care for future patients facing similar situations.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients of both sexes admitted to the Poison control center, Ain Shams university hospitals with acute hydrocarbon toxicity during the duration from December 2023 till December 2024 with a maximum number of 60 cases within 24 hours of intoxication.
• Exclusion Criteria:
• Patients with these criteria will be excluded:
• • Cases \> 24 hours of intoxication.
• • Cases with occupational exposure to hydrocarbons.
• • Pregnant females.
• • Any cases received any treatment before arrival to the PCC.
• • Cases suffering from cardiac, respiratory, renal, hepatic or haematological disorders.
• • Cases presenting with fever.
• • Cases with other causes that can increase levels of CRP \& pro-calcitonin as bacterial infection, recent major trauma, major burn ,septic shock and medullary thyroid cancer.