Intensive Versus Standard Treatment for Spinal Anesthesia-induced Hypotension in Preeclamptic Patients

Launched by GENERAL HOSPITAL OF NINGXIA MEDICAL UNIVERSITY · Nov 28, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how different blood pressure targets during spinal anesthesia affect the health of newborns when women with a condition called preeclampsia undergo cesarean sections. Preeclampsia can cause high blood pressure during pregnancy, and managing this condition is critical for both the mother and baby. The researchers want to find out if keeping blood pressure at specific levels can lead to better outcomes for the babies born.

To participate in this trial, women must be between 18 and 45 years old, either having their first baby or already having had children, and be at least 32 weeks pregnant with one baby. They should be scheduled for a cesarean section using spinal anesthesia. However, women with certain health issues, such as very high blood pressure or specific weight concerns, cannot join. If eligible, participants will be monitored closely during their surgery to help researchers understand how different blood pressure management strategies can affect both their health and the health of their newborns.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 18-45 years
• • Primipara or multipara
• • Singleton pregnancy ≥32 weeks
• • American Society of Anesthesiologists physical status classification I to III
• • Scheduled for cesarean section under spinal anesthesia
• Exclusion Criteria:
• • Baseline blood pressure ≥160 mmHg
• • Body height \< 150 cm
• • Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
• • Eclampsia or chronic hypertension
• • Hemoglobin \< 7g/dl
• • Fetal distress, or known fetal developmental anomaly