90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients

Launched by GENERAL HOSPITAL OF NINGXIA MEDICAL UNIVERSITY · Nov 28, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how effective a medication called phenylephrine is in preventing low blood pressure that can happen after spinal anesthesia during cesarean sections in pregnant women with a condition called preeclampsia. Preeclampsia is a serious health issue that can affect both the mother and baby, and the trial aims to find the right dose of phenylephrine that works well for these patients.

To be eligible for this study, participants should be women aged 18 to 45 who are having their first or later baby and are at least 32 weeks pregnant. They should be scheduled for a cesarean section using spinal anesthesia and generally healthy according to a specific medical classification. However, women with very high blood pressure, certain health conditions, or other specific factors will not be able to participate. Those who join the trial can expect to receive careful monitoring and treatment during their procedure to help ensure their safety and the safety of their baby. This trial is not yet recruiting participants, so there will be more information available once it starts.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 18-45 years
• • Primipara or multipara
• • Singleton pregnancy ≥32 weeks
• • American Society of Anesthesiologists physical status classification I to III
• • Scheduled for cesarean section under spinal anesthesia
• Exclusion Criteria:
• • Baseline blood pressure ≥160 mmHg
• • Body height \< 150 cm
• • Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
• • Eclampsia or chronic hypertension
• • Hemoglobin \< 7g/dl
• • Fetal distress, or known fetal developmental anomaly