90% Effective Dose of Norepinephrine Infusions Under Intensive and Standard Treatment

Launched by GENERAL HOSPITAL OF NINGXIA MEDICAL UNIVERSITY · Nov 28, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the use of norepinephrine infusions to prevent low blood pressure after spinal anesthesia during cesarean sections. The researchers want to find out the right dose of norepinephrine that is effective for most patients while they are receiving either intensive or standard treatment. The trial is not yet recruiting participants, but it will focus on women aged 18 to 45 who are about to have a cesarean section and are in good health.

To be eligible for the trial, women must be at least 18 years old, be having their first or another baby, and be at least 37 weeks pregnant. However, those with certain health issues, like very high blood pressure or specific weight limits, cannot participate. If you join the trial, you can expect close monitoring and care during and after your surgery to ensure your safety and comfort. This study aims to improve how we manage blood pressure during these important medical procedures.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 18-45 years
• • Primipara or multipara
• • Singleton pregnancy ≥37 weeks
• • American Society of Anesthesiologists physical status classification I to II
• • Scheduled for cesarean section under spinal anesthesia
• Exclusion Criteria:
• • Body height \< 150 cm
• • Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
• • Eclampsia or chronic hypertension or baseline blood pressure ≥180 mmHg
• • Hemoglobin \< 7g/dl
• • Fetal distress, or known fetal developmental anomaly