90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment

Launched by GENERAL HOSPITAL OF NINGXIA MEDICAL UNIVERSITY · Nov 28, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at a medication called phenylephrine, which is used to help prevent low blood pressure after spinal anesthesia during cesarean sections. The goal is to find out the most effective dose of this medication when given through an infusion. This study will focus on women between the ages of 18 and 45 who are having their first or subsequent baby, are at least 37 weeks pregnant, and are scheduled for a cesarean delivery using spinal anesthesia.

To participate, women must meet certain health criteria, like having a normal weight and no serious health issues that could complicate the surgery. Participants will receive the phenylephrine infusion during their procedure and will be monitored to see how well it works in preventing low blood pressure. It’s important to note that this trial is not yet recruiting participants, so those interested will need to wait for it to start.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 18-45 years
• • Primipara or multipara
• • Singleton pregnancy ≥37 weeks
• • American Society of Anesthesiologists physical status classification I to II
• • Scheduled for cesarean section under spinal anesthesia
• Exclusion Criteria:
• • Body height \< 150 cm
• • Body weight \> 100 kg or body mass index (BMI) ≥ 40 kg/m2
• • Eclampsia or chronic hypertension or baseline blood pressure ≥180 mmHg
• • Hemoglobin \< 7g/dl